Publications & Clinical Research

Key studies studies that validate the efficacy and accuracy of their Ventripoint technology for cardiac volume and function measurement across various patient groups, including pediatric and congenital heart disease cases. It showcases their commitment to evidence-based medicine, featuring research that demonstrates the correlation and reliability of their Knowledge-Based Reconstruction (KBR) compared to traditional methods like MRI and 3D echocardiography.

Comparing a knowledge-based 3D reconstruction algorithm to TomTec 3D echocardiogram algorithm in measuring left cardiac chamber volumes in the pediatric population

This study demonstrates that there is a very good correlation between knowledge-based (VMS 3.0+) and 3D (Tomtec) algorithms when measuring 3D echocardiography-derived LA and LV volumes in pediatric patients. The time (mins) to analyze volumes using VMS were less than using Tomtec.

Real-time 3D-echocardiography of the right ventricle—paediatric reference values for right ventricular volumes using knowledge-based reconstruction: a multicentre study

This study demonstrates that calculation of ventricular volumes by KBR allows reliable non-invasive assessment of right ventricular volumes with excellent intra- and interobserver variations. The calculated percentiles based on a large paediatric population serve as a reference and may facilitate the use of real-time 3D echocardiography for the analysis of right ventricular size and function.

EuroEcho 2018 - Application of Knowledge-Based Reconstruction to Three Dimensional Echocardiography and Comparison with Semiautomatic Border Detection Method for Evaluating Ventricular Function in Tetralogy of Fallot

ASE 2019 - Determination of LV volume and ejection fraction with a novel 3D knowledge based reconstruction technique in comparison with contrast echocardiography measurements

This study demonstrates clinical feasibility of quantifying ventricular volumes and function using VMS+ on native 3DE datasets from normal and repaired TOF hearts. Analyses times with semiautomatic detection for the LV, however for the RV, VMS+ analysis times were longer. RV volumes obtained by VMS+ were greater than those by semiautomatic border detection, likely due to better outflow tract inclusion with VMS+.

Knowledge-based 3D reconstruction compared to MRI for evaluation of right ventricular volumes and function in congenital heart diseases affecting the right ventricle

The study concluded the use of the Ventripoint knowledge based reconstruction technique revealed no significant differences in the measurement of ventricular volumes or EF in comparison to contrast echocardiography measurements.

Accuracy and Test-Retest Reproducibility of Two-Dimensional Knowledge-Based Volumetric Reconstruction of the Right Ventricle in Pulmonary Hypertension

Two-dimensional KBR is an accurate, novel technique for RV volumetric quantification in PH, with superior test-retest reproducibility compared with conventional 2D echocardiographic RV FAC